Sildalis ED Medication: Side Effects, Dosage, Price, Alternatives

Updated on February 28th, 2024 | Nizagara Online Labs
sildalis ed medication


Sildenafil and Tadalafil
Erectile Dysfunction Medication

Sildalis is an ED medication containing two active ingredients, Sildenafil 100mg and Tadalafil 20mg. Common side effects of Sildalis include headaches, nausea, flushes, stuffy nose, dizziness. It comes as tablets and available in one 120 milligrams strength. Sildalis tablets require 30–60 minutes to take effect, regardless of the dose you are taking. The effects of Sildalis last up to 4 hours. Sildalis used to treat erectile dysfunction and works by increasing blood flow to the penis, which helps to have and keep an erection.

What is Sildalis?

Sildalis is a combination medication containing both sildenafil citrate (the active ingredient in Viagra) and tadalafil (the active ingredient in Cialis) used to treat erectile dysfunction (ED) in one single tablet.

Is Sildalis a Viagra or Cialis?

No, Sildalis is not Viagra or Cialis – it is a separate medication that combines the active ingredients of both Viagra (sildenafil citrate) and Cialis (tadalafil) into a single tablet for treating erectile dysfunction.

What are the ingredients in Sildalis?

The ingredients of Sildalis contain PDE5 inhibitor Sildenafil citrate and Tadalafil.

What are other forms of Sildalis?

The other forms of Sildalis are Sildalist and Sildalist Strong.

What are the Side Effects of Sildalis?

Common side effects of Sildalis are listed below.

  • Headache
  • Dizziness
  • Blurred vision
  • Nausea
  • Sneezing
  • Bone pain
  • Chest pain
  • Allergy
  • Ringing in ears
  • Diarrhea
  • Heartburn
  • Upset stomach
  • Back pain
  • Flushing
  • Hearing loss
  • Low blood pressure
  • Nosebleeds
  • Rectal bleeding
  • Priapism
  • Prolonged erection
  • Trouble breathing
  • Anxiety
  • Cardiovascular
  • Difficulty in concentrating

What is Sildalis dosage for ED?

Sildalis dosage for erectile dysfunction is 120mg. The standard recommended starting dose of Sildalis is 120mg. The dose is adjusted based on individual effectiveness, the person’s age, overall health, tolerance, and the severity of the disease.

Sildalis vs. Viagra: What Are the Key Differences?

The key differences between Sildalis and Viagra are listed in the table below.

Medication FactorsSildalis (sildenafil and tadalafil)Viagra (sildenafil)
Dosages120mg200 milligrams, 150mg, 130mg, 120mg, 100 milligrams, 50mg, 25mg
AvailabilityOnline pharmaciesLocal and online pharmacies
AppearanceRedBlue, diamond-shaped pill
Onset30 minutes30 minutes
Maximum effect45–120 minutes45–60 minutes
Lasts as long as3–36 hours3–5 hours
Affected by food?Yes, take it 1 to 2 hours after eating, or with a low-fat meal.Yes, take it 1 to 2 hours after eating, or with a low-fat meal.
Most common side effectsBack pain, Diarrhea, Dyspepsia, Flushing, Headache, Myalgia, Nasal congestion, Nausea, Upset stomach, Vision changesHeadache, flushing, nasal congestion, upset stomach, vision changes

How long does Sildalis last?

The effects of Sildalis last up to 36 hours, contingent on the individual person’s metabolism, the dosage administered, and whether the medication is consumed with or without food.

How does Sildalis work?

Sildalis works by helping to relax muscles and arteries inside the penis, which helps more blood reach the penis. The combination of sexual arousal, relaxation and increased blood flow helps fill the penis with blood.

Sexual arousal leads to the release of nitric oxide (NO) in the blood vessels of the penis. Nitric oxide is a signaling molecule that relaxes and dilates the blood vessels in the penis. This relaxation of blood vessels allows increased blood flow into the erectile tissues of the penis, leading to an erection.

The active pharmaceutical ingredients in Sildalis are sildenafil citrate and tadalafil. Tadalafil and Sildenafil are phosphodiesterase type 5 (PDE5) inhibitors. PDE5 inhibition enables accumulation of cyclic guanosine monophosphate (cGMP) in penile tissue for an extended duration by blocking cGMP degradation. Persistent cGMP activation relaxes smooth muscles to increase blood flow, facilitating erection.

How to take Sildalis?

Take one dose of Sildalis approximately 30 minutes to 1 hour before sexual activity, ideally on an empty stomach. Seek immediate medical attention if an erection exceeds 4 hours (a condition referred to as priapism), as this constitutes a medical emergency.

Can I take two Sildalis tablets in one day?

Taking two Sildalis tablets in one day is not recommended without the guidance of a healthcare provider.

Who can take Sildalis?

Men aged 18 and over can take Sildalis for Erectile Dysfunction.

Can women take Sildalis?

No, females can’t take Sildalis. Sildalis is approved to treat ED in men. It’s not approved for use in women, and studies have mixed results. Seven “Female Viagra” medications, including Lady Era, Femalegra, Lovegra, Cenforce FM, Ladygra, Womenra, and Addyi (Flibanserin), have been approved to treat sexual dysfunction in certain women.

Who should not take Sildalis?

People with uncontrolled heart problems or rare eye conditions need to avoid Sildalis in certain cases. Adults ages 65 years and older, and some people with liver or kidney problems, have a higher risk of experiencing Sildalis side effects. Sildalis should never be taken with nitrates or riociguat (Adempas).

Sildalis Interactions

Sildalis interacts with other medications, potentially impacting their effectiveness, increasing side effects, or intensifying their severity.

What affects the effectiveness of Sildalis?

8 things that affect the effectiveness of Sildalis are listed below.

  1. ED drugs: Avanafil (Avana), Tadalafil (Cialis), Vardenafil (Levitra) or Udenafil (Zudena)
  2. Drugs to treat high blood pressure or a prostate disorder
  3. Antibiotics, such as clarithromycin, erythromycin, or telithromycin
  4. Antifungal medicine: ketoconazole or itraconazole
  5. Medicine to treat HIV/AIDS: atazanavir, indinavir, ritonavir, or saquinavir
  6. Nitrates
  7. Medications used to treat pulmonary artery hypertension
  8. Over-the-counter medicines, foods, vitamins, and herbal products

What foods to avoid when taking Sildalis?

Avoid consuming fatty meals, grapefruit or grapefruit juice, and alcohol on the days when you intend to take Sildalis. A high-fat meal delays its onset of action, impacting the overall duration of effectiveness. Excessive alcohol consumption impairs the medication’s efficacy.

Does alcohol affect Sildalis?

Yes, alcohol affects Sildalis. Alcohol counteracts the medication’s effects and worsens side effects, such as headaches and flushing.

What are alternatives to Sildalis?

Sildalis alternatives are Tadasiva, Silvitra, Tadapox.

1. Tadaisva

Tadasiva is a combination drug used for treating erectile dysfunction (ED) in men. It contains two active pharmaceutical ingredients – tadalafil which inhibits the PDE5 enzyme to improve blood flow to the penis, and vardenafil which prevents the breakdown of cGMP to achieve a similar effect. By incorporating both these compounds in one tablet, Tadasiva offers a synergistic mechanism leading to harder, more sustainable erections when a man is sexually aroused.

2. Silvitra

Silvitra is a combination drug containing two active pharmaceutical ingredients – sildenafil citrate and vardenafil hydrochloride. Sildenafil blocks the PDE5 enzyme, leading to higher cGMP levels and increased blood flow, while vardenafil works similarly but through slightly different molecular mechanisms. By incorporating both these compounds, Silvitra leverages their complementary effects to provide enhanced efficacy in treating erectile dysfunction with a single tablet.

3. Tadapox

Tadapox is a combination medication containing two active ingredients – tadalafil and dapoxetine – that work synergistically to treat both erectile dysfunction and premature ejaculation. Tadalafil works as a PDE5 inhibitor, enhancing blood flow to the penis to improve erection quality, while dapoxetine is a short-acting SSRI that helps delay ejaculation by modulating serotonin signaling. By providing this dual mechanism of action, Tadapox offers men struggling with sexual performance an integrated solution that aims to help them last longer while maintaining firm, sustained erections during intimacy.